Stimulation of Neuronal Acetylcholine Receptors Induces Rapi…

Highly Cited

755
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1986
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  • DOI 10.1126/science.3749894
  • PMID https://pubmed.ncbi.nlm.nih.gov/3749894
  • OpenAlex ID W2016773845
  • Type Article
  • Language EN
  • Published 03 Oct 1986
  • Volume 234 (4772)
  • Pages 80–83
  • Source Science
  • Publisher American Association for the Advanc…
  • FWCI 14.57
  • Countries 1
  • Institutions 2
  • Added 24 Jun 2016
  • Updated 30 Oct 2026
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Stimulation of Neuronal Acetylcholine Receptors Induces Rapid Gene Transcription

Article 1986 EN

Cholinergic agonists rapidly and transiently induced transcription of the c-fos protooncogene and one or more actin genes in neuronally differentiated PC12 cells. Transcription was activated within minutes after stimulation of the nicotinic acetylcholine receptor and required an influx of extracellular Ca2+ ions through voltage-sensitive calcium channels. Nicotine activation proceeded by a differe…

755

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27

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3

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14.57

FWCI

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3 authors
#AuthorInstitutionsORCID
1 Michael E. Greenberg NYU Langone Health (US) New York University (US)
2 Edward Benjamin Ziff NYU Langone Health (US) New York University (US)
3 Lloyd A. Greene NYU Langone Health (US) New York University (US)
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