Long-term ACE Inhibition Doubles Lifespan of Hypertensive Ra…
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- DOI 10.1161/01.cir.96.9.3164
- PMID https://pubmed.ncbi.nlm.nih.gov/9386189
- OpenAlex ID W2009359363
- Type Article
- Language EN
- Published 04 Nov 1997
- Volume 96 (9)
- Pages 3164–3172
- Source Circulation
- Publisher Lippincott Williams & Wilkins
- FWCI 4.80
- Added 24 Jun 2016
- Updated 14 Oct 2026
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Long-term ACE Inhibition Doubles Lifespan of Hypertensive Rats
Article 1997 EN
BACKGROUND: We compared the outcome of lifelong treatment with the ACE inhibitor ramipril in young prehypertensive stroke-prone spontaneously hypertensive rats (SHR-SP) and age-matched normotensive Wistar-Kyoto (WKY) rats. Ramipril was given in an antihypertensive and subantihypertensive dose. In addition to the primary end point, lifespan, surrogate parameters such as cardiac left ventricular hyp…
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1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Wolfgang Linz | — | — |
| 2 | Timm Jessen | — | — |
| 3 | Reinhard H.A. Becker | — | |
| 4 | Bernward A. Schölkens | — | — |
| 5 | Gabriele Wiemer | — | — |
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