Islet Amyloid Polypeptide in Human Insulinomas: Evidence for…

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1994
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  • DOI 10.2337/diab.43.2.329
  • PMID https://pubmed.ncbi.nlm.nih.gov/8288058
  • OpenAlex ID W2007959627
  • Type Article
  • Language EN
  • Published 01 Feb 1994
  • Volume 43 (2)
  • Pages 329–336
  • Source Diabetes
  • Publisher American Diabetes Association
  • FWCI 6.33
  • Countries 1
  • Institutions 2
  • Added 24 Jun 2016
  • Updated 16 Oct 2026
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Islet Amyloid Polypeptide in Human Insulinomas: Evidence for Intracellular Amyloidogenesis

Article 1994 EN

Amyloid deposits that characteristically form in the pancreatic islets of patients with non-insulin-dependent diabetes mellitus (NIDDM) and in insulinomas are both derived from islet amyloid polypeptide (IAPP). Evidence from previous studies has suggested that deposition of IAPP-derived amyloid is related to inherent amyloidogenic sequences present within normal human IAPP, together with an increa…

94

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6.33

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5 authors
#AuthorInstitutionsORCID
1 Timothy D. O’Brien University of Minnesota (US) Mayo Clinic (US)
2 Alexandra E. Butler University of Minnesota (US) Mayo Clinic (US)
3 Patrick C. Roche University of Minnesota (US) Mayo Clinic (US)
4 Kenneth H. Johnson University of Minnesota (US) Mayo Clinic (US) —
5 Peter C. Butler University of Minnesota (US) Mayo Clinic (US)
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