Human γ‐interferon expression in the mammary gland of transg…

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1993
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Human γ‐interferon expression in the mammary gland of transgenic mice

Article 1993 EN

Transgenic mice carrying a hybrid gene consisting of ovine beta-lactoglobulin gene sequences and human gamma-interferon (hIFN-g) cDNA were produced. hIFN-g expression in the mammary gland of two lactating transgenic founder females was found. The concentration of active hIFN-g in the milk was estimated as being ca. 1800 IU/ml. The hIFN-g ability to express in the mammary gland was found in the pro…

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6

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6 authors
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1 Vasily N. Dobrovolsky Russian Academy of Sciences (RU) Institute of Bioorganic Chemis… (RU)
2 Oleg V. Lagutin Institute of Bioorganic Chemis… (RU) —
3 Tatiana V. Vinogradova Institute of Bioorganic Chemis… (RU) —
4 И. С. Фролова Gamalei Institute of Epidemiol… (RU)
5 В П Кузнецов Gamalei Institute of Epidemiol… (RU) —
6 O. A. Larionov Corresponding Institute of Bioorganic Chemis… (RU) —

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