Anti-oxidative neuroprotection by estrogens in mouse cortica…

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Anti-oxidative neuroprotection by estrogens in mouse cortical cultures

Article 2000 EN Bronze

Estrogen replacement therapy in postmenopausal women may reduce the risk of Alzheimer's disease, possibly by ameliorating neuronal degeneration. In the present study, we examined the neuroprotective spectrum of estrogen against excitotoxicity, oxidative stress, and serum-deprivation-induced apoptosis of neurons in mouse cortical cultures. 17beta-estradiol as well as 17alpha-estradiol and estrone a…

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4 authors
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1 Yeong Hee Bae University of Ulsan (KR) —
2 Jee Yeon Hwang University of Ulsan (KR) —
3 Yang Hee Kim University of Ulsan (KR)
4 Jae Young Koh University of Ulsan (KR) —

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