Protective action of 17β‐estradiol and tamoxifen on glutamat…
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- DOI 10.1016/s0736-5748(99)00097-0
- PMID https://pubmed.ncbi.nlm.nih.gov/10715583
- OpenAlex ID W1992741307
- Type Article
- Language EN
- Published 09 Mar 2000
- Volume 18 (2-3)
- Pages 289–297
- Source International Journal of Developmental N…
- Publisher Wiley
- FWCI 3.11
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 31 Oct 2026
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Protective action of 17β‐estradiol and tamoxifen on glutamate toxicity in glial cells
Article 2000 EN
Estrogens influence differentiation, growth and function of neurons, but less is known of their effects on glia. In our experiments reported here, the ovarian steroid, 17beta-estradiol, and the "designer", non-steroidal estrogen, tamoxifen, effectively protected C-6 glioma 2B clone cells from the cytotoxicity of the excitatory neurotransmitter, glutamate. Exposure of these cells to 10-20 mM glutam…
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1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Hogan Shy | University of California, Berk… (US) | — |
| 2 | Latha M. Malaiyandi | University of California, Berk… (US) | |
| 3 | Paola S. Timiras Corresponding | University of California, Berk… (US) | — |
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