INHIBITION OF INDUCIBLE NITRIC OXIDE SYNTHASE AMELIORATES FU…

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INHIBITION OF INDUCIBLE NITRIC OXIDE SYNTHASE AMELIORATES FUNCTIONAL AND HISTOLOGICAL CHANGES OF ACUTE LUNG ALLOGRAFT REJECTION1,2

Article 1997 EN

BACKGROUND: We recently demonstrated that inhibition of inducible nitric oxide synthase (iNOS) ameliorated severe acute lung allograft rejection. This study used a rat lung transplant model to determine (1) the time course and cellular localization of iNOS expression during the histological progression of unmodified acute rejection and (2) whether inhibition of iNOS prevented impaired gas exchange…

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8 authors
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1 Neil K. Worrall National Institutes of Health (US) Washington University in St. L… (US) —
2 Carlos Henrique Ribeiro Boasquevisque Washington University in St. L… (US) —
3 Mitchell D. Botney Washington University in St. L… (US) —
4 Thomas P. Misko Monsanto (United States) (US)
5 Patrick M. Sullivan Monsanto (United States) (US)
6 Jon H. Ritter —
7 Thomas Bruce Ferguson Washington University in St. L… (US)
8 George Alexander Patterson Corresponding Washington University in St. L… (US) —

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