Adenoprotection of the heart involves phospholipase C-induce…
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- DOI 10.1152/ajpheart.00247.2009
- PMID https://pubmed.ncbi.nlm.nih.gov/19525381
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/2724201
- OpenAlex ID W1990059632
- Type Article
- Language EN
- Published 13 Jun 2009
- Volume 297 (2)
- Pages H718–H725
- Source American Journal of Physiology-Heart and…
- Publisher American Physical Society
- FWCI 1.36
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 28 Oct 2026
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Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-ε to RACK2 in adult rat and mouse
Article 2009 EN Green
Adenosine protects the heart from adrenergic overstimulation. This adenoprotection includes the direct anti-adrenergic action via adenosine A(1) receptors (A(1)R) on the adrenergic signaling pathway. An indirect A(1)R-induced attenuation of adrenergic responsiveness involves the translocation of PKC-epsilon to t-tubules and Z-line of cardiomyocytes. We investigated with sarcomere imaging, immunocy…
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5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Richard A. Fenton | University of Massachusetts Ch… (US) | — |
| 2 | Satoshi Komatsu | University of Massachusetts Ch… (US) | |
| 3 | Mitsuo Ikebe | University of Massachusetts Ch… (US) | |
| 4 | Lynne G. Shea | University of Massachusetts Ch… (US) | — |
| 5 | James G. Dobson | University of Massachusetts Ch… (US) |
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