High-Level Expression of Human Lactoferrin in Milk of Transg…

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High-Level Expression of Human Lactoferrin in Milk of Transgenic Mice Using Genomic Lactoferrin Sequence

Article 1999 EN

In our previous study, transgenic mice were generated that expressed human lactoferrin (hLF) in milk using cDNA under control of the 2 kb bovine beta-casein promoter. The expression level of the protein in milk of 7 mice ranged from 1 to 200 microg/ml; 1 to 34 microg/ml in 6 mice and 200 microg/ml in 1 mouse. With the aim of inducing higher expression of the protein, we constructed an expression c…

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12 authors
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1 S. J. Kim Korea Research Institute of Bi… (KR) —
2 Bo Hwa Sohn Korea Research Institute of Bi… (KR) —
3 S. Jeong Korea Research Institute of Bi… (KR) —
4 K.-W. Pak Korea Research Institute of Bi… (KR) —
5 J.-S. Park Korea Research Institute of Bi… (KR) —
6 Il‐Kyu Park Korea Research Institute of Bi… (KR)
7 Tae‐Hoon Lee Korea Research Institute of Bi… (KR)
8 Yun-Hee Choi Korea Research Institute of Bi… (KR) —
9 C.-S. Lee Korea Research Institute of Bi… (KR) —
10 Yong‐Mahn Han Korea Research Institute of Bi… (KR)
11 D.-Y. Yu Korea Research Institute of Bi… (KR) —
12 K.-K. Lee Corresponding Korea Research Institute of Bi… (KR) —

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