Nanoscale Organization of the MEC-4 DEG/ENaC Sensory Mechano…

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Nanoscale Organization of the MEC-4 DEG/ENaC Sensory Mechanotransduction Channel inCaenorhabditis elegansTouch Receptor Neurons

Article 2007 EN Hybrid

Hearing, touch and proprioception are thought to involve direct activation of mechano-electrical transduction (MeT) channels. In Caenorhabditis elegans touch receptor neurons (TRNs), such channels contain two pore-forming subunits (MEC-4 and MEC-10) and two auxiliary subunits (MEC-2 and MEC-6). MEC-4 and MEC-10 belong to a large superfamily of ion channel proteins (DEG/ENaCs) that form nonvoltage-…

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1 Juan G. Cueva Stanford Medicine (US) Stanford University (US) —
2 Atticus Mulholland Stanford Medicine (US) Stanford University (US) —
3 Miriam B. Goodman Corresponding Stanford Medicine (US) Stanford University (US)

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