Role of endothelin in the maintenance of blood pressure in c…
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- DOI 10.1161/01.cir.90.5.2510
- PMID https://pubmed.ncbi.nlm.nih.gov/7955209
- OpenAlex ID W1963565312
- Type Article
- Language EN
- Published 01 Nov 1994
- Volume 90 (5)
- Pages 2510–2518
- Source Circulation
- Publisher Lippincott Williams & Wilkins
- FWCI 8.49
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 22 Oct 2026
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Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan).
Article 1994 EN Bronze
BACKGROUND: Endothelin (ET) is a potent vasoconstrictor, and its concentration is increased in patients with heart failure. The purpose of this study was to investigate the role of endothelin in heart failure by use of a rat model. METHODS AND RESULTS: Experiments were performed on rats at 1 through 16 weeks after sham operation or coronary artery ligation. Rats with left ventricular end-diastolic…
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6 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | John R. Teerlink | F. Hoffmann-La Roche AG (CH) | |
| 2 | B M Löffler | F. Hoffmann-La Roche AG (CH) | — |
| 3 | Patrick Hess | F. Hoffmann-La Roche AG (CH) | — |
| 4 | Jean-Paul Maire | F. Hoffmann-La Roche AG (CH) | — |
| 5 | Martine Clozel | F. Hoffmann-La Roche AG (CH) | — |
| 6 | Jean‐Paul Clozel | F. Hoffmann-La Roche AG (CH) | — |
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