The alveolar macrophage delivery system. Kinetic studies in cultured explants of murine lung.

The production of alveolar macrophages in a blood-free organ culture system has been studied to determine whether free macrophages undergo mitosis or whether their ongoing production is dependent upon continuing division of interstitial cells. Explants of murine long were attached to cellophane or glass; after 6 days of culture, a population of cells identified morphologically and functionally as…