Investigation of potential topoisomerase I inhibitors from i…

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  • DOI 10.1096/fasebj.28.1_supplement.975.8
  • OpenAlex ID W1591679280
  • Type Article
  • Language EN
  • Published 01 Apr 2014
  • Volume 28 (S1)
  • Source The FASEB Journal
  • Publisher Wiley
  • Countries 1
  • Institutions 1
  • Added 24 Jun 2016
  • Updated 22 Sep 2026
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Investigation of potential topoisomerase I inhibitors from indigenous natural products in southwestern region of Nigeria (975.8)

Article 2014 EN

Polyphenolic compounds are important secondary metabolites that may serve as anti‐tumour agents by binding the nuclear enzymes topoisomerase I thereby affecting DNA function and cell survival. Polyphenols from sixteen hypothesized antitumour plants in the south western region of Nigeria were screened for topoisomerase I inhibition in comparison to camptothecin. Partially purified bulky polyphenols…

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UN Sustainable Development Goals
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5 authors
#AuthorInstitutionsORCID
1 Olubunmi Abiola Magbagbeola University of Lagos (NG) —
2 Ayorinde Babatunde James University of Lagos (NG)
3 Selina Omolola Odesanmi University of Lagos (NG) —
4 Titilola Aderonke Samuel University of Lagos (NG)
5 Temitope Oshodi University of Lagos (NG) —
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