Understanding and Ameliorating the TTR Amyloidoses

Emerging


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  • DOI 10.1002/9780470572702.ch45
  • OpenAlex ID W1516633015
  • Type Other
  • Language EN
  • Published 09 Jun 2010
  • Pages 967–1003
  • Countries 1
  • Institutions 2
  • Added 10 Oct 2025
  • Updated 16 Oct 2026
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Understanding and Ameliorating the TTR Amyloidoses

Other 2010 EN

This chapter contains sections titled: Overview Introduction to Amyloid Diseases Introduction to Transthyretin Mechanism of TTR Amyloidogenesis Ttr Amyloidogenesis Occurs by a Downhill Polymerization Current Understanding of the Etiology of the TTR Amyloid Diseases Influence of the Cellular Proteostasis Network on TTR Amyloidogenesis Disease-Associated TTR Mutants are Thermodynamically Less Stable…

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7 authors
#AuthorInstitutionsORCID
1 Steven M. Johnson Scripps Research Institute (US)
2 R. Luke Wiseman Scripps Research Institute (US)
3 Johan F. Paulsson Scripps Research Institute (US) Harvard University (US)
4 Sungwook Choi Scripps Research Institute (US)
5 Evan T. Powers Scripps Research Institute (US)
6 Joel N. Buxbaum Scripps Research Institute (US)
7 Jeffery W. Kelly Scripps Research Institute (US)

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