RB
Robert F. Bruns

Elite Scholar

96
Works
8,257
Citations
42
H-Index
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Author Statistics
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Robert F. Bruns

Also known as: Bruns, Robert F., R F Bruns, R. F. BRUNS, R. F. Bruns, R.F. Bruns

96

Total Works

8,257

Citations

42

H-Index

67

i10-Index

Citation & Works Trend by Year
34 years active
Top Research Topics
Receptor Mechanisms and Signaling (53) Adenosine and Purinergic Signaling (53) Neuroscience and Neuropharmacology Research (28) Biochemical and Molecular Research (26) Neuropeptides and Animal Physiology (17)
Recent Publications
15 shown
Year Publication Title Citations Action
2023 Effects of DPTQ, a novel positive allosteric modulator of the dopamine D1 receptor, on spontaneous eye blink rate and spatial working memory in the nonhuman primate Psychopharmacology 3
2022 Mutual Cooperativity of Three Allosteric Sites on the Dopamine D1 Receptor Molecular Pharmacology 10
2019 CCDC 1944256: Experimental Crystal Structure Determination The Cambridge Structural Database 0
2019 CCDC 1944255: Experimental Crystal Structure Determination The Cambridge Structural Database 0
2019 CCDC 1944257: Experimental Crystal Structure Determination The Cambridge Structural Database 0
2019 Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Positive Allosteric Modulator of the Human Dopamine D1 Receptor Journal of Medicinal Chemistry 55
2019 Positive allosteric modulators of the dopamine D1 receptor: A new mechanism for the treatment of neuropsychiatric disorders Advances in pharmacology 41
2018 Intracellular Binding Site for a Positive Allosteric Modulator of the Dopamine D1 Receptor Molecular Pharmacology 39
2017 Preclinical profile of a dopamine D1 potentiator suggests therapeutic utility in neurological and psychiatric disorders Neuropharmacology 49
2016 An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis Journal of Pharmacology and Experimental Therapeutics 46
2016 In Vitro Characterization of a Novel Allosteric Potentiator of the Dopamine D1 Receptor The FASEB Journal 1
2016 Behavioral Effects of a Novel Allosteric Potentiator of the Dopamine D1 Receptor in Human D1 Knock‐in Mice and Rhesus Monkeys The FASEB Journal 2
2016 Neurochemical Profile of a Novel Allosteric Potentiator of the Dopamine D1 Receptor The FASEB Journal 1
2012 Rules for Identifying Potentially Reactive or Promiscuous Compounds Journal of Medicinal Chemistry 342
2006 Azetidinones as vasopressin V1a antagonists Bioorganic & Medicinal Chemistry 74

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